TGFدر? Gene Expression as a Biomarker of Bronchiolar and Alveola

TGFدر? Gene Expression as a Biomarker of Bronchiolar and Alveolar Duct Epithelium Modulate by HIIT Exercise Training با word دارای 8 صفحه می باشد و دارای تنظیمات در microsoft word می باشد و آماده پرینت یا چاپ است
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توجه : در صورت مشاهده بهم ریختگی احتمالی در متون زیر ،دلیل ان کپی کردن این مطالب از داخل فایل ورد می باشد و در فایل اصلی TGFدر? Gene Expression as a Biomarker of Bronchiolar and Alveolar Duct Epithelium Modulate by HIIT Exercise Training با word،به هیچ وجه بهم ریختگی وجود ندارد
بخشی از متن TGFدر? Gene Expression as a Biomarker of Bronchiolar and Alveolar Duct Epithelium Modulate by HIIT Exercise Training با word :
سال انتشار : 1394
نام کنفرانس یا همایش : همایش بین المللی یافته های نوین پژوهشی در علوم ورزشی
تعداد صفحات : 8
چکیده مقاله:
The effect of mitogenic biomarkers on epithelial cells and their role in promoting the dramatic proliferative in the bronchiolar and alveolar duct epithelium in response to regular physical activity is not clear. So the aim of this study was to investigate TGF- gene expression as a biomarker of bronchiolar and alveolar duct epithelium modulate by HIIT exercise training. Twenty-four middle-aged men (age: 45 ± 5 years, VO2max: 34.8ml/kg/min, body fat: 26.25%) were volunteered in this study and randomly divided into control (n=12) and exercise (n=12) groups. The exercise group performed eight weeks HIIT exercise training 3 days a week (30 min/day) on the treadmill by 60% (HR max) on the first weeks until 90% (HR max) on the last weeks. Participants blood samples, body composition, VO2 max and transforming growth factor- gene expression was measured 24 hours before and after the training program. Bio Easy Master Mix Kit and real-time PCR method used for TGF- gene expression. Our data have been analyzed by independent t-test on SPSS software. The result showed that high intensity interval training can change gene expression. TGF- gene expression showed reduced significantly in the exercise group compared to control group (p<0.001) as,bronchiolar and alveolar duct epithelium abnormalities has decreased (2-C T = -8/2). The present study on middleaged men supports a prevent role of exercise training on pathological and physiological alveolar duct epithelium abnormalities through modulate of TGF- gene expression.
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